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                                         Coenzyme Q10

Coenzyme Q10 (CoQ10 or Ubiquinone) is a vitamin-like compound, that can be found in most  aerobe living organisms, from bacteria to mammals. The compound was identified in 1940, and then in 1957 in the United States, Dr. F. Crane successfully isolated it from cattle heart mithochondrium (which is the energy producing center of the cells). In 1958 its exact chemical structure was determined, later it was artificially synthesized successfully by fermentation. Its clinical application began in Japan, in 1960, at that time only in connection with the treatment of circulatory problems. Owing to the promising results, by the 1970s a row of clinical scientists started studying the properties of Q10, and the problems caused by its deficiency, and they took a survey of its beneficial effects on other areas as well. In 1978 Dr. Peter Mitchell received a Nobel Prize for describing the effect-mechanism of CoQ10.
 
Chemically, ubiquinones are composed of two units, a so called benzoquinone and a so called terpenoid part. CoQ10 absorbs slowly following oral intake. It is absorbed by the aid of so called chylomicrons, is divided up in the liver, then binds to VLDL cholesterol (very low-density lipoprotein). It reaches a peak quantity in blood 5-4 hours following ingestion. Its half-period of degradation is 34 hours, and is eliminated primarily through the bile. Characteristically, it can be found in high concentration in organs where much energy is needed, for example; the heart, kidneys and pancreas. It is a curiosity that it has a lower concentration in the myocardial cells of patients suffering in cardiac failure.
 
CoQ10 plays an important role in several physiological processes. It plays a prominent role  in respiratory chain in interenzymatic electron transport, that is in the energy supply of cells. It is important to note that CoQ10 is not a stimulant, but a substance synthesized in every cell of our body, which is indispensable for the energy producing processes at the cellular level.

CoQ10 helps to achieve increased working capacity and youthful energy; in addition most people experience an improved general well-being. Its membrane-stabilizing effect is also worth mentioning, and we should not forget about one of its most important qualities: being an excellent antioxidant, it helps in blocking the harmful oxidative processes in our body and in binding free radicals as well.
 
With advancement of age, the “endogenous” CoQ10 production of the body decreases. We obtain coenzyme from our daily diet as well (see the CoQ10 content of some common foods in the table below). In addition to food, some high quality dietary supplements are available as well for adequate CoQ10 amounts. It is especially important in situations throughout life when we need exuberant energy levels (stress, increased physical/mental strain), or when the amounts ingested with food decrease (for example in elderly age, or in the case of slimming diets or fasting).
 
CoQ₁₀ content of some foods**